Open AccessNutritional Formulation for Patients with Angelman Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study of Exogenous Ketones
Author(s) -
Robert P. Carson,
Donn L Herber,
Zhaoxing Pan,
Fenna T. Phibbs,
Alexandra P. Key,
Arnaud Gouelle,
Patience Ergish,
Eric Armour,
Shital M. Patel,
Jessica Duis
Publication year - 2021
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxab284
Subject(s) - angelman syndrome , double blind , placebo , medicine , randomized controlled trial , pediatrics , chemistry , biochemistry , alternative medicine , pathology , gene
Angelman syndrome (AS) patients often respond to low glycemic index therapy to manage refractory seizures. These diets significantly affect quality of life and are challenging to implement. These formulations may have benefits in AS even in the absence of biomarkers suggesting ketosis.
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