Open AccessIntermittent Bolus Compared With Continuous Feeding Enhances Insulin and Amino Acid Signaling to Translation Initiation in Skeletal Muscle of Neonatal Pigs
Author(s) -
Agus Suryawan,
Samer W. ElKadi,
Hanh V. Nguyen,
Marta L. Fiorotto,
Teresa A. Davis
Publication year - 2021
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxab190
Subject(s) - skeletal muscle , endocrinology , bolus (digestion) , medicine , insulin , amino acid , translation (biology) , biology , chemistry , biochemistry , messenger rna , gene
Nutrition administered as intermittent bolus feeds rather than continuously promotes greater protein synthesis rates in skeletal muscle and enhances lean growth in a neonatal piglet model. The molecular mechanisms responsible remain unclear.
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