Open AccessNeonatal Piglets Can Synthesize Adequate Creatine, but Only with Sufficient Dietary Arginine and Methionine, or with Guanidinoacetate and Excess Methionine
Author(s) -
O. Chandani Dinesh,
Thillayampalam Kankayaliyan,
M. Rademacher,
Christopher Tomlinson,
Robert F. Bertolo,
Janet A. Brunton
Publication year - 2020
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.1093/jn/nxaa369
Subject(s) - creatine , methionine , arginine , metabolite , amino acid , biochemistry , chemistry , glycine , medicine , endocrinology , biology
Suckling piglets synthesize most of their creatine requirement, which consumes substantial amounts of arginine in order to synthesize guanidinoacetic acid (GAA) and methionine in order to transmethylate GAA to creatine.
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