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Pleomorphic carcinomas of the lung are rare malignant biphasic tumors composed of carcinomatous and sarcomatous components. The carcinomatous component is usually an adenocarcinoma or a squamous cell carcinoma, and the sarcomatous component is usually a spindle cell carcinoma. Recently, we encountered two patients who underwent surgery for pleomorphic carcinoma whose carcinomatous component was large cell neuroendocrine carcinoma.

Combined Large Cell Neuroendocrine Carcinoma and Spindle Cell Carcinoma of the Lung