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Genetic polymorphisms associated with breast cancer risk are likely to differ among ethnic and molecular subtypes. The ability to identify genetic polymorphisms affecting the risk of estrogen receptor (ER)-positive breast cancer may lead to the more efficient selection of candidates for chemoprevention with endocrine agents. We focused on identifying common genotypes for ER-positive breast cancer in premenopausal Japanese women.

japanese journal of clinical oncology

Possible Difference in Frequencies of Genetic Polymorphisms of Estrogen Receptor , Estrogen Metabolism and P53 Genes Between Estrogen Receptor-positive and -negative Breast Cancers