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Background:  Transforming growth factor-β (TGF-β) is capable of affecting the proliferation of many cell types. βIGH3, TGF-β inducible gene, was originally isolated from lung adenocarcinoma cell line (A549). We have hypothesized that βIGH3 mRNA levels could be predictors of the development and invasion of lung cancer.

βIGH3, a TGF-β Inducible Gene, is Overexpressed in Lung Cancer