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Background:  Serum pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP) is a metabolite of type I collagen comprising 90% or more of organic substances in bone. Its usefulness as a marker of bone metastasis from malignant tumors is expected.

Usefulness of Serum Carboxy-Terminal Telopeptide of Type I Collagen (ICTP) as a Marker of Bone Metastasis from Lung Cancer