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Background:  The main form of cytotoxic treatment for advanced Hodgkin’s disease (HD) is conventional dose multiagents chemotherapy. As HD is not common in Japan, we conducted a phase II study of the commonly used combination chemotherapy (CCT) regimen established in the West for Japanese patients with advanced HD to confirm the efficacy and safety.

japanese journal of clinical oncology

Alternating Combination Chemotherapy C-MOPP (Cyclophosphamide, Vincristine, Procarbazine, Prednisone) and ABVd (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) in Clinical Stage II–IV Hodgkin’s Disease: a Multicenter Phase II Study (JCOG 8905)