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We aimed to gain a better understanding of how standardization of laboratory data can impact predictive model performance in multi-site datasets. We hypothesized that standardizing local laboratory codes to logical observation identifiers names and codes (LOINC) would produce predictive models that significantly outperform those learned utilizing local laboratory codes.

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An argument for reporting data standardization procedures in multi-site predictive modeling: case study on the impact of LOINC standardization on model performance