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Summary  A sensitive molecular assay was developed to quantify male and female  Plasmodium falciparum  gametocytes. Its application in 2 clinical trials demonstrates that the early effects of primaquine may be due to gametocyte fitness rather than sex ratio.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

A Molecular Assay to Quantify Male and Female Plasmodium falciparum Gametocytes: Results From 2 Randomized Controlled Trials Using Primaquine for Gametocyte Clearance