A Novel Ligand of Toll-like Receptor 4 From the Sheath of Wuchereria bancrofti Microfilaria Induces Proinflammatory Response in Macrophages | Zendy

Suprabhat Mukherjee | Zendy; Sandip Mukherjee | Zendy; Tushar Kanti Maiti | Zendy; Samir Bhattacharya | Zendy; Santi P. Sinha Babu | Zendy

Open Access

A Novel Ligand of Toll-like Receptor 4 From the Sheath of Wuchereria bancrofti Microfilaria Induces Proinflammatory Response in Macrophages

Author(s) -

Suprabhat Mukherjee,

Sandip Mukherjee,

Tushar Kanti Maiti,

Samir Bhattacharya,

Santi P. Sinha Babu

Publication year - 2017

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jix067

Subject(s) - wuchereria bancrofti , proinflammatory cytokine , biology , tlr4 , cd64 , lymphatic filariasis , immunology , toll like receptor , macrophage , inflammation , cd163 , brugia malayi , receptor , immune system , filariasis , antigen , innate immune system , helminths , biochemistry , in vitro

Lymphatic filariasis, frequently caused from Wuchereria bancrofti infection, is endemic in several parts of the globe and responsible for human health problems and socioeconomic loss to a large extent. Inflammatory consequences originating from host-parasite interaction play a major role in the disease pathology and allied complications. The identity of the key mediator of this process is yet unknown in filarial research.

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