Open AccessThe Use of Quinacrine in Nitroimidazole-resistant Giardia Duodenalis: An Old Drug for an Emerging Problem
Author(s) -
Ana RequenaMéndez,
Pilar Goñi,
Encarnación Rubio Aranda,
Diana Pou,
Victòria Fumadó,
Silvia Lóbez,
Edelweiss Aldasoro,
Juan Cabezos,
María Eugenia Valls,
Begoña Treviño,
Antonio Federico Martínez Montseny,
Antonio Clavel,
Joaquím Gascón,
José Muñóz
Publication year - 2017
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jix066
Subject(s) - giardia , metronidazole , nitroimidazole , giardia lamblia , refractory (planetary science) , medicine , gastroenterology , microbiology and biotechnology , drug resistance , biology , antibiotics , pathology , astrobiology
There is little evidence regarding the management of refractory giardiasis after treatment with nitroimidazoles. This study estimates the proportion of persistent giardiasis in 3 hospitals in Barcelona, describes associated risk factors and genotype, and evaluates the efficacy rate of quinacrine in those with persistent giardiasis.
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