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TO THE EDITOR—We read with interest the recent article by von Dach et al [1] on the comparative genomics of communityacquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in Switzerland. Von Dach et al nicely highlight what remains one of the great biological and epidemiological conundrums regarding the spread of CA-MRSA, which is that the same strain can cause an epidemic in one geographic location and fail to spread in another despite multiple introductions and a high volume of travel between locations. The failure of the

Global Spread of the Community-Associated Methicillin-ResistantStaphylococcus aureusUSA300 Latin American Variant