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Antibodies to the cysteine-rich domain II of Plasmodium vivax Duffy binding protein (PvDBP) can inhibit binding of this parasite ligand to its receptor on red blood cells, the Duffy antigen/receptor for chemokines. These binding-inhibitory antibodies (BIAbs) also inhibit P. vivax invasion of reticulocytes in vitro.

Naturally Acquired Binding-Inhibitory Antibodies toPlasmodium vivaxDuffy Binding Protein and Clinical Immunity to Malaria in Rural Amazonians