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Enterotoxigenic Escherichia coli (ETEC) is a globally prevalent cause of diarrhea. Though usually self-limited, it can be severe and debilitating. Little is known about the host transcriptional response to infection. We report the first gene expression analysis of the human host response to experimental challenge with ETEC.

Transcriptomic Analysis of the Host Response and Innate Resilience to EnterotoxigenicEscherichia coliInfection in Humans