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Despite the relevance of monocytes as promoters of the inflammatory response, whether human immunodeficiency virus (HIV) infection induces premature age-related changes to the phenotype and function of monocytes or whether these alterations are different and/or specifically driven by HIV remains to be mechanistically determined.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Phenotype and Polyfunctional Deregulation Involving Interleukin 6 (IL-6)– and IL-10–Producing Monocytes in HIV-Infected Patients Receiving Combination Antiretroviral Therapy Differ From Those in Healthy Older Individuals