Open AccessDownregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients
Author(s) -
M. C. Lanteri,
Farnaz Vahidnia,
Shuping Tan,
Jack T. Stapleton,
Philip J. Norris,
Joseph Heitman,
X. Deng,
Sheila M. Keating,
Donald Brambilla,
MP Busch,
Brian Custer,
for the NHLBI REDS III Study,
for the NHLBI REDS III Study,
Sharon A. Glynn,
Donald Brambilla,
Sarah R. Sullivan,
MP Busch,
P. J. Norris,
M. C. Lanteri,
Farnaz Vahidnia,
J. Heitman,
X. Deng,
Sheila M. Keating,
B. Custer,
Shuishi Tan,
Jack T. Stapleton
Publication year - 2014
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiu660
Subject(s) - downregulation and upregulation , chemokine , blood transfusion , immunology , medicine , transmission (telecommunications) , human immunodeficiency virus (hiv) , virology , inflammation , biology , computer science , gene , telecommunications , biochemistry
An association between GB virus C (GBV-C) and improved outcomes of human immunodeficiency virus (HIV) infection has been reported in HIV-positive individuals with active GBV-C coinfection. This study provides insights into the immune mechanisms underlying the protective role of GBV-C in HIV-infected patients.
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