Open AccessField Evaluation of a Real-Time Fluorescence Loop-Mediated Isothermal Amplification Assay, RealAmp, for the Diagnosis of Malaria in Thailand and India
Author(s) -
Jaymin C. Patel,
Naomi W. Lucchi,
Pallavi Srivastava,
J. T. Lin,
Rungniran Sugaram,
Supannee Aruncharus,
Praveen K. Bharti,
Man Mohan Shukla,
Kanungnit Congpuong,
Wichai Satimai,
Niraj Kumar Singh,
Venkatachalam Udhayakumar,
Steven R. Meshnick
Publication year - 2014
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiu252
Subject(s) - loop mediated isothermal amplification , malaria , virology , transmission (telecommunications) , fluorescence , loop (graph theory) , isothermal process , medicine , biology , physics , computer science , immunology , genetics , optics , telecommunications , mathematics , dna , thermodynamics , combinatorics
To eliminate malaria, surveillance for submicroscopic infections is needed. Molecular methods can detect submicroscopic infections but have not hitherto been amenable to implementation in surveillance programs. A portable loop-mediated isothermal amplification assay called RealAmp was assessed in 2 areas of low malaria transmission.
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