English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

transmission within family units is common, and natural infection with RSV, especially in very young infants, does not provide solid immunity against reinfection. These data that were collected in rural Kenya are consistent with another household study performed more than 40 years ago in Rochester, New York, that reported 2 months of surveillance data [5]. Although it would be useful to have more data from different geographic and climatic settings, the congruity of these 2 studies suggests the likelihood that these results are a realistic reflection of how RSV is transmitted within family units globally. Importantly, the current study was prospective, employed active surveillance, and used modern diagnostic techniques such as polymerase chain reaction (PCR) and viral isolate sequencing to confirm temporal transmission patterns. The investigators showed that transmission of an infant’s first RSV infection was most often attributed to school-age children in the household. This report exemplifies the importance of understanding the epidemiological details of how a contagious respiratory pathogen spreads within a community. Indeed, understanding transmission dynamics may be a key factor in defining strategies that can successfully protect infants from RSV infection. In addition to using this information to emphasize the importance of handwashing and avoiding large particle aerosol and fomite transmission, it may be useful to ask how understanding transmission dynamics can inform vaccine development strategies. In particular, we should explore the potential target populations for RSV immunization.

Protecting the Family to Protect the Child: Vaccination Strategy Guided by RSV Transmission Dynamics