Open AccessDecreased Interleukin 7 Responsiveness of T Lymphocytes in Patients With Idiopathic CD4 Lymphopenia
Author(s) -
Camille E. Puronen,
William L. Thompson,
Hiromi Imamichi,
Stéphanie Beq,
Jessica N. Hodge,
Catherine Rehm,
Raphaëlle Parker,
Rebecca DerSimonian,
Jason M. Brenchley,
Irini Sereti
Publication year - 2012
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jis219
Subject(s) - immunology , interleukin 2 , interleukin , medicine , cytokine
Elevated serum interleukin 7 (IL-7) levels are observed in lymphopenic conditions, including idiopathic CD4 lymphopenia (ICL), which is characterized by CD4 lymphopenia in the absence of human immunodeficiency virus infection or other known immunodeficiency.
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