Gene Polymorphism in Toll-like Receptor 4: Effect on Antibody Production and Persistence After Acellular Pertussis Vaccination During Adolescence
Author(s) -
Kirsi GröndahlYliHannuksela,
Juho Vuovirta,
AlexMikael Barkoff,
M. Viander,
Olivier Van Der Meeren,
Jussi Mertsola,
Qiushui He
Publication year - 2012
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jis182
Subject(s) - pertussis toxin , bordetella pertussis , vaccination , pertactin , immunology , medicine , antibody , pertussis vaccine , filamentous haemagglutinin adhesin , booster dose , whooping cough , biology , receptor , immunization , genetics , g protein , bacteria
Toll-like receptors play an important role in the regulation of adaptive immunity. This study aimed to investigate whether Toll-like receptor 4 (TLR4) polymorphisms influence the production and persistence of antibodies after acellular pertussis booster vaccination during adolescence.
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