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Although evidence supports a relationship between human immunodeficiency virus (HIV)-1 exposure and HIV-1-specific CD8(+) T cell responses, studies have not demonstrated a direct association between the quantity of HIV-1 to which a person is exposed and the presence or absence of a response.

Breast Milk HIV-1 RNA Levels and Female Sex Are Associated With HIV-1-Specific CD8+ T-Cell Responses in HIV-1-Exposed, Uninfected Infants in Kenya