Open AccessC21orf91 Genotypes Correlate With Herpes Simplex Labialis (Cold Sore) Frequency: Description of a Cold Sore Susceptibility Gene
Author(s) -
John D. Kriesel,
Brandt Jones,
Nori Matsunami,
Milan K. Patel,
Christine A. St. Pierre,
Evelyn A. KurtJones,
Robert W. Finberg,
Mark Leppert,
Maurine R. Hobbs
Publication year - 2011
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jir633
Subject(s) - genetics , candidate gene , single nucleotide polymorphism , biology , population , transmission disequilibrium test , herpes simplex virus , genotype , gene , linkage disequilibrium , genetic linkage , snp , virus , medicine , environmental health
Herpes simplex virus type 1 (HSV-1) infects >70% of the United States population. We identified a 3-megabase region on human chromosome 21 containing 6 candidate genes associated with herpes simplex labialis (HSL, "cold sores").
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