Open AccessSoluble CD163, a Novel Marker of Activated Macrophages, Is Elevated and Associated With Noncalcified Coronary Plaque in HIV-Infected Patients
Author(s) -
Tricia H. Burdo,
Janet Lo,
Suhny Abbara,
Jeffrey Wei,
Michelle E. DeLelys,
Fred Preffer,
Eric Rosenberg,
Kenneth C. Williams,
Steven Grinspoon
Publication year - 2011
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jir520
Subject(s) - cd163 , human immunodeficiency virus (hiv) , monocyte , macrophage , immunology , medicine , inflammation , virus , virology , pathology , biology , in vitro , biochemistry
Pro-inflammatory monocytes/macrophages may contribute to increased atherosclerosis in human immunodeficiency virus (HIV)-infected patients. We investigate--to our knowledge, for the first time--sCD163 and other markers of monocyte activation in relationship to atherosclerotic plaque in HIV-infected patients.
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