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Background Syphilis is a chronic systemic infectious disease that is subject to acute outbreaks and latency periods when left untreated. It is an infectious disease produced by a bacteria, Treponema pallidum, of predominantly sexual transmission. The inclusion of syphilis in pregnancy as a sexually transmitted infection with compulsory notification is justified by its high prevalence rate and high vertical transmission rate, which ranges from 30% to 100% without adequate treatment. Congenital syphilis is a result of the hematogenous spread of Treponema pallidum, an untreated or inadequately treated pregnant woman, through the placenta, which causes miscarriages or child and fetal deaths. Our objective was to draw an epidemiological profile of women, living in Belém / PA, notified by syphilis during pregnancy and who developed infant or fetal death in 2017 and 2018. Methods This is a descriptive epidemiological study. Two information systems were used, the Mortality Information System (MIS) and the Notification Record Information System (NRIS). At MIS, all child and fetal deaths of residents of Belém in 2017 and 2018 were selected. In NRIS, we selected all cases of pregnant women notified by syphilis in 2017 and 2018, also resident in the municipality. Subsequently, the two banks were compared to verify whether pregnant women notified for syphilis evolved with infant or fetal death. Data were analyzed according to age, race, education, gestational period, length of treatment of pregnant women, whether the partner was treated and the type of death of the children. Results We found 32 women with reports of syphilis in pregnant women, of whom 81% developed fetal death and 19% had infant death. 63% were between 20 and 29 years old, 88% were brown, 75% were in the third trimester of pregnancy when they were notified, 25% had incomplete elementary school and 25% had incomplete high school. 72% were treated with 7,200,000 IU of Penicillin G Benzathine. 59% of cases were not performed in the treatment of the partner. Conclusions Most of these women are young, poorly educated, and despite appropriate treatment, their partners have not been treated and may have been reinfected and passed on the infection to their children. Key messages Syphilis in pregnant women; Hild and fetal death

53Women with syphilis notification in pregnant women who lose their baby, belém/pa, 2017 and 2018