Effects of human adipose-derived stem cells on the regeneration of damaged visceral pleural mesothelial cells: a morphological study in a rabbit model
Author(s) -
Young-Du Kim,
Young Joon Jun,
Jeana Kim,
Chi Kyung Kim
Publication year - 2014
Publication title -
interactive cardiovascular and thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 56
eISSN - 1569-9293
pISSN - 1569-9285
DOI - 10.1093/icvts/ivu124
Subject(s) - medicine , mesothelial cell , stem cell , cd90 , mesothelium , adipose tissue , pathology , mesenchymal stem cell , cd34 , parietal pleura , regeneration (biology) , lung , biology , microbiology and biotechnology
Although an alveolar air leak (AAL) after pulmonary resection is a troublesome complication that diminishes a patient's quality of life and increases medical costs, current treatment and preventive methods for AAL are not effective. Therefore, we transplanted adipose-derived stem cells (ASCs) to the damaged visceral pleura to facilitate the regeneration of mesothelial cells and investigated the possibility of cell therapy as a treatment option for AAL.
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