Leg ischaemia before circulatory arrest alters brain leucocyte count and respiratory chain redox state | Zendy

Fredrik Yannopoulos | Zendy; Oiva Arvola | Zendy; Henri Haapanen | Zendy; Johanna Herajärvi | Zendy; Ilkka Miinalainen | Zendy; Hanna Jensen | Zendy; Kai Kiviluoma | Zendy; Tatu Juvonen | Zendy

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Leg ischaemia before circulatory arrest alters brain leucocyte count and respiratory chain redox state

Author(s) -

Fredrik Yannopoulos,

Oiva Arvola,

Henri Haapanen,

Johanna Herajärvi,

Ilkka Miinalainen,

Hanna Jensen,

Kai Kiviluoma,

Tatu Juvonen

Publication year - 2013

Publication title -

interactive cardiovascular and thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 56

eISSN - 1569-9293

pISSN - 1569-9285

DOI - 10.1093/icvts/ivt415

Subject(s) - medicine , circulatory system , ischemia , anesthesia , perfusion , pathology , cardiology

Remote ischaemic preconditioning and its neuroprotective abilities are currently under investigation and the method has shown significant effects in several small and large animal studies. In our previous studies, leucocyte filtration during cardiopulmonary bypass reduced cerebrocortical adherent leucocyte count and mitigated cerebral damage after hypothermic circulatory arrest (HCA) in piglets. This study aimed to obtain and assess direct visual data of leucocyte behaviour in cerebral vessels after hypothermic circulatory arrest following remote ischaemic preconditioning.

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