Open AccessIn vivo oxygen, temperature and pH dynamics in the female reproductive tract and their importance in human conception: a systematic review
Author(s) -
Ka Ying Bonnie Ng,
Roel Mingels,
Hywel Morgan,
Nick Macklon,
Ying Cheong
Publication year - 2017
Publication title -
human reproduction update
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.977
H-Index - 180
eISSN - 1362-4946
pISSN - 1355-4786
DOI - 10.1093/humupd/dmx028
Subject(s) - female reproductive tract , in vivo , oxygen , dynamics (music) , reproductive tract , biology , chemistry , psychology , endocrinology , microbiology and biotechnology , uterus , pedagogy , organic chemistry
Despite advances in ART, implantation and pregnancy rates per embryo transfer still remain low. IVF laboratories strive to ensure that the process of handling gametes in vitro closely mimics the in vivo environment. However, there remains a lack of knowledge regarding the in vivo regulation and dynamic variation in biophysical parameters such as oxygen concentration, pH and temperature within the reproductive tract.
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