Open AccessA 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity
Author(s) -
Éric Ravussin,
Leanne M. Redman,
James Rochon,
Sai Krupa Das,
Luigi Fontana,
William E. Kraus,
Sergei Romashkan,
Donald A. Williamson,
Simin Nikbin Meydani,
Dennis T. Villareal,
Steven R. Smith,
Richard I. Stein,
Tammy Scott,
Tiffany M. Stewart,
Edward Saltzman,
Samuel Klein,
Manju Bhapkar,
Corby K. Martin,
Cheryl H. Gilhooly,
John O. Holloszy,
Evan C. Hadley,
Susan B. Roberts,
for the CALERIE Study Group
Publication year - 2015
Publication title -
the journals of gerontology series a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.134
H-Index - 189
eISSN - 1758-535X
pISSN - 1079-5006
DOI - 10.1093/gerona/glv057
Subject(s) - calorie restriction , weight loss , weight change , randomized controlled trial , medicine , quality of life (healthcare) , calorie , triiodothyronine , body mass index , basal metabolic rate , adverse effect , endocrinology , zoology , physiology , biology , obesity , thyroid , nursing
Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in many species. The implications for humans can be clarified by randomized controlled trials of CR.
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