Open AccessProgression of White Matter Hyperintensities of Presumed Vascular Origin Increases the Risk of Falls in Older People
Author(s) -
Michele L. Callisaya,
Richard Beare,
Thanh G. Phan,
Leigh Blizzard,
Amanda G. Thrift,
Jian Chen,
Velandai Srikanth
Publication year - 2014
Publication title -
the journals of gerontology series a
Language(s) - English
Resource type - Journals
eISSN - 1758-535X
pISSN - 1079-5006
DOI - 10.1093/gerona/glu148
Subject(s) - hyperintensity , medicine , gait , white matter , affect (linguistics) , cardiology , physical medicine and rehabilitation , psychology , magnetic resonance imaging , radiology , communication
Greater volume of cerebral white matter hyperintensities (WMH) of presumed vascular origin may affect postural control and gait. WMH measured at one time point predicts an increased risk of incident multiple falls. However, it is unknown whether WMH progression increases falls risk. We hypothesized that the progression of WMH would be associated with a greater risk of multiple falls.
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