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Biological evidence suggests that vitamin D might be involved in regulating mood. The relationship between 25-hydroxyvitamin D (25OHD) and the onset of depressive symptoms was examined over a 4.4-year follow-up in a sample of older adults.

Serum 25-Hydroxyvitamin D and the Onset of Late-Life Depressive Mood in Older Men and Women: The Pro.V.A. Study