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Results of cross-sectional analyses of the association of kidney function with bone mineral density (BMD) have been conflicting. We examined the association of cystatin-C, a new marker of kidney function that is unrelated to lean mass, with initial and follow-up BMD, in an ancillary study of the Cardiovascular Health Study, a population-based cohort of individuals &gt; or = 65 years old.

Kidney Function Predicts the Rate of Bone Loss in Older Individuals: The Cardiovascular Health Study