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Catecholamine release is a marker of stress, and high plasma norepinephrine levels have been associated with increased mortality. The predictive value of high urinary catecholamine excretion for functional decline and mortality in healthier older persons has not been determined.

the journals of gerontology. series a, biological sciences and medical sciences

High Urinary Catecholamine Excretion Predicts Mortality and Functional Decline in High-Functioning, Community-Dwelling Older Persons: MacArthur Studies of Successful Aging