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Family doctors are generalise: any experience which an individual perceives as problematic can become the legitimate concern of a GP, if it is brought up in a consultation. One of the fundamental tasks of the GP is to interpret a person's story. Here, the doctor tries to establish if the person's sense of unease suggests the onset of a discrete identifiable disease, or has its origins in other forms of stress, for example, personal unhappiness or unfavourable socio-economic circumstances.1 In the process, the doctor may draw on biomedical diagnostic pathways, for example, for the patient who describes symptoms of polyuria and polydypsia, and has a blood sugar concentration of 16 mmols/1. But at other times, the GP may have to bypass confident biomedical diagnosis, and adopt a decision pathway which approximates more to symptomatic treatment.2 Often, GPs do not make biomechanical diagnoses: dealing with non-disease and non-diagnosis is a routine part of a GP's work.3-4

How can evidence-based medicine help patients in general practice?