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Background Usage rate of cigarette, alcohol, and substance is increasing day by day.Protectiv efactors have primary importance for prevention of substance use.The aim of this study is to investigate the prevalance of using cigarette, alcohol and substance and research relationship between risk factories and substance using, among high school students. Methods Ä°n Malatya city there are 17866 Anatolian, 14381 Vocational,10362 Religious high school students.Totally all of this 42629 students form the universe of this cross-sectional study. When the prevalance of using cigarette accepted as 25 % in high school students; sample size in Anatolian high school,Occupatioanal high school and Religious high school was found 283, 283 and 280 respectively.This survey was conducted in 9 different high schools which choosed by stratified sampling method, and 975 high school students have been reached in this survey.Ä°n the statistical analysing of data,Chi square test, logistic regression test were used. Results The prevalance of cigarette, alcohol and substance using found 34%, 14.3% and 4.2% respectivey among students participating in the survey.Cigarette using; in male students is 2.2 times higher (Cl 95%,1.661-3.073), in alcohol users is 7.6 times higher(Cl 95%,4.919-11.834)(p &amp;lt; 0.05).Alcohol using is 9.6 times higher(Cl 95%, 5.712-16.250) in cigarette smokers(p &amp;lt; 0.05).And alcohol using in students with alcohol use in their families is 26.8 times higher(Cl 95%,12.489-57.711)(p &amp;lt; 0.05).Substance using; found 12.2 times higher(Cl 95%,4.900-30.566) in alcohol users,2.4 times higher(Cl 95%,5.712-16.250) in cigarette smokers and 5.6 times higher(Cl 95%,1.366-23.068)in students with substance use in their families (p &amp;lt; 0.05). Conclusions Cigarette using is more common in males and alcohol users.Alcohol use increses in smokers and students with alcohol use in their families.Substance use among students increases when student uses cigarette or alcohol and if there are substanceuse in their families. Key messages Alcohol use increses in smokers, smoking increses in alcohol users. Substance use increses in smokers, alcohol users and in the students with substance use in their families.

Prevalance of Using Cigarette,Alcohol,Substance Among High School Students and Factors Affected Them