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Background Previous studies on economic recessions and mortality due to cancer and other chronic diseases have yielded inconsistent findings. We investigated the trend in all-disease mortality and mortality due to several specific diseases before and during the Great Recession of 2008 in individuals who were employed in 2001, at the beginning of follow-up. Methods We follow in a nationwide longitudinal study over 15 million subjects who had a job in Spain in 2001. The analysed outcomes were mortality at ages 25–64 years due to all diseases, cancer and other chronic diseases. We calculated annual mortality rates from 2003 to 2011, and the annual percentage change (APC) in mortality rates during 2003–07 and 2008–11, as well as the effect size, measured by the APC difference between the two periods. Results All-disease mortality increased from 2003 to 2007 in both men and women; then, between 2008 and 2011, all-disease mortality decreased in men and reached a plateau in women. In men, the APC in the all-disease mortality rate was 1.6 in 2003–07 and −1.4 in 2008–11 [effect size −3.0, 95% confidence interval (CI) −3.7 to −2.2]; in women it was 2.5 and −0.3 (effect size −2.8, 95% CI −4.2 to −1.3), respectively. Cancer mortality and mortality due to other chronic diseases revealed similar trends. Conclusions In the group of individuals with a job in 2001 the Great Recession reversed or stabilized the upward trend in all-disease mortality.

Trends in disease mortality before and during the Great Recession in individuals employed in Spain in 2001