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Since 1981, when the first cases of human immunodeficiency virus (HIV) infection were diagnosed, the need to monitor what emerged shortly afterwards as an epidemic arose. Portugal was not immune, and over the years different measures have been taken to control the national epidemic. The goal of this research is to contribute to the previous knowledge about the trend of HIV infection at the regional level that allows adequate planning focused on controlling the epidemic. This is an observational, descriptive and cross-sectional study, whose data were anonymized at the source, based on the analysis of cases notified by doctors. The data were analyzed using the software Microsoft® Excel version 16.16.4 and IBM® SPSS® Statistics version 25. To check if there is a proven statistical relationship between the variables, the Chi-Square independence test (X2) was used. The results obtained revealed 14512 accumulated cases, in the different stages of infection, 76.7% of which are male, with a higher incidence between 25-29 years of age. Type HIV-1 covers 97.1% of all cases. From 2013 to 2017 it was observed that 74.2% lived in urban areas. Late diagnosis was found in rural areas, particularly in heterosexual transmission. It was concluded that there are several similarities between data at regional and national levels, such as the occurrence of late diagnosis in the category of heterosexual transmission. Regarding legislative changes, no conclusion can be inferred, although hypotheses were raised that can should be discussed in future studies. Key messages Late diagnosis in rural areas. Late diagnosis in heterosexual transmission.

HIV/AIDS: a 30 year history at the Northern Region of Portugal