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Background Public health problems often constitute so called “wicked problems”, and the importance of involving multiple stakeholders in order to address such problems is acknowledged, for instance through the SDG17 guidelines. Partnerships between academia and the public sector have been deemed especially promising. However, sustainable partnerships might be difficult due to divergent understandings and interests. Although there is a substantial research literature on academic-public partnerships in general, partnerships addressing public health specifically are less investigated. The aim of the project was therefore to identify enablers for sustainable public health partnerships between academia and the public sector. Methods A mixed methods design was used. A survey regarding partnerships was sent to 41 European, Asian and American regions, with a response rate of 72 %. Based on survey data, an interview guide was developed and four best cases (Canada, Bulgaria, the Netherlands and Norway) were identified. Site visits and group interviews with representatives from stakeholders of the partnerships were conducted. Interview data and answers to open ended questions from questionnaires were analysed. Results Three main findings became apparent through the analysis. Important enablers were: 1) person-to-person fit between individuals, 2) national incentive schemes for collaboration, and 3) formal partnership agreements that provided a framework that allowed for manoeuvring. The enablers identified are on a macro, miso and micro level. Furthermore, they can be categorised as political, organisational, and social. Conclusions The data support the notion that partnerships are complex social structures that need to be initiated and managed on different levels and with different measures. At the same time, data demonstrate that across different geographical, political, and social contexts the same enablers are reappearing as important for sustaining public health partnerships. Key messages Similar enablers for sustaining public health partnerships are found across geographical, political, and social contexts. Important enablers for partnerships are person-to-person fit, national incentive schemes, and formal agreements.

Sustainable public health partnerships: Results from 41 European, Asian and American regions