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Background Depression is a significant mental health problem which tends to be one of the leading causes of disability worldwide. Depression can lead to suicide and is the second leading cause of death in 15 - 29 year olds globally. Psychological morbidity in undergraduate students represents a neglected public health problem and holds major implications for campus health services and mental policy making. This study was therefore carried out to assess knowledge of depression, prevalence of depression and accuracy of depression status among students of the Faculty of Pharmacy and College of Medicine of the University of Lagos. Methods This was a descriptive cross-sectional study carried out among students on the College of Medicine campus of the University of Lagos. Multi-stage sampling technique was used to select the participants while data were collected using a self-administered questionnaire. Data was analysed using Epi info 7.0. Chi-square test was used to analyse categorical variables where p &amp;lt; 0.05 is statistically significant. Results A total of 400 students across all departments were recruited for this study. Most students were in 18 - 21 years' age group, with almost same proportion of females to males. More than half (56.50%) of the students had good knowledge of depression. The overall prevalence of depression was 36.5% among the students out of which 18.2% portrayed severe depression. More than half of the respondents (54.9%) who perceive they are depressed were actually not depressed. There was statistically significant difference between perceived depressed state and actual depressed state among the students (X2 = 18.14; p = 0.0001) Conclusions More than half the students possessed a good knowledge of depression. About one third were actually depressed. It is therefore important to create awareness programs which can serve as a platform to increase the knowledge and also reduce the prevalence of depression among these students. Key messages Understanding how much students know about depression will help to fill the identified knowledge gap and prevent them from going into depression. Identifying depressed students will help to alert campus health services to manage these students and thereby prevent potential problems associated with depression like suicide or school drop out.

Knowledge and prevalence of depression among students on College of Medicine University of Lagos