Open AccessNon-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes
Author(s) -
Christopher Villongco,
David E. Krummen,
Jeffrey H. Omens,
Andrew D. McCulloch
Publication year - 2016
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/euw356
Subject(s) - medicine , cardiac resynchronization therapy , cardiology , left bundle branch block , qrs complex , ventricular dyssynchrony , heart failure , bundle branch block , electrocardiography , ejection fraction
Left ventricular activation delay due to left bundle branch block (LBBB) is an important determinant of the severity of dyssynchronous heart failure (DHF). We investigated whether patient-specific computational models constructed from non-invasive measurements can provide measures of baseline dyssynchrony and its reduction after CRT that may explain the degree of long-term reverse ventricular remodelling.
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