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Sudden cardiac death (SCD) risk prediction has substantial limitations. The Regional Restitution Instability Index (R2I2) is a promising new ECG-based biomarker of SCD. R2I2 uses the surface 12-lead ECG to quantify regional heterogeneity of electrical restitution, a property of ventricular myocardium implicated in arrhythmogenesis. We investigated the potential of a combined R2I2 and amino-terminal pro-B-type natriuretic peptide (NT-proBNP) SCD risk marker in an ischaemic cardiomyopathy cohort.Peer-reviewedPost-printHeart Rhythm Congress, HRC2014, Birmingham, U

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5Improving sudden cardiac death risk stratification in patients with ischaemic cardiomyopathy: a combined electrocardiogram and plasma biomarker approach