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In patients with advanced heart failure (HF) and prolonged QRS interval, cardiac resynchronization therapy (CRT) reduces symptoms and risk of death. The added benefit of an implantable cardioverter defibrillator (ICD) remains questionable in some patients.

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Relationship between New York Heart Association class change and ventricular tachyarrhythmia occurrence in patients treated with cardiac resynchronization plus defibrillator