Open AccessSystemic inflammatory changes after pulmonary vein radiofrequency ablation do not alter stem cell mobilization
Author(s) -
Andreas Stein,
G. Weßling,
Isabel Deisenhofer,
Gillian L. Busch,
Birgit Steppich,
H. Estner,
Bernhard Zrenner,
Claus Schmitt,
S Braun,
Albert Schömig,
Ilka Ott
Publication year - 2008
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/eun041
Subject(s) - medicine , radiofrequency ablation , pulmonary vein , atrial fibrillation , ablation , mobilization , progenitor cell , cardiology , necrosis , vein , stem cell , genetics , history , archaeology , biology
Aim of this study was to investigate the number of circulating progenitor cells, systemic inflammatory mediators, and myocardial necrosis in patients with paroxysmal atrial fibrillation (AF) undergoing pulmonary vein (PV) isolation by radiofrequency (RF) ablation. Radiofrequency ablation generates a localized myocardial necrosis that might result in a release of inflammatory mediators enhancing progenitor cell mobilization and improving tissue repair.
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