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Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Dijon Football Côte d"Or OnBehalf CLEO-CD Background Lifestyle behaviours (LB) are keystones of coronary prevention and might be impacted during Covid-19 (C19) lockdown. Purpose To compare the LB in urban and rural patients suffering from chronic coronary syndrom (CCS) Methods 250 outpatients suffering from CCS were invited during the 6th week of the 1st C19 lockdown to answer to a phone-call questionnaire. Results 220 questionnaires were fit for analysis, of whom about 1/4 declared a psychologic impairment; people staying at home in urban zones trended to be more impacted. Unhealthier behaviours including cigarette smoking, decrease in physical activity and increase in screentime were common, especially in patients from urban zones. Telehealth partially counterbalanced limitation in care access and none declared discontinuation of medications. Conclusion The lockdown impacted wellbeing of CCS patients; living in rural zone was associated with a healthier LB. Main results TOTAL URBAN RURAL N (%) 220 107 113 p * Age (years, SD) 66.4+/-12.0 64.5+/-14.0 68.2+/-9.5 0.02 Male/Female 154/66 76/31 78/35 0.77 Alone at home 47(21.7) 28(26.2) 19(17.3) 0.13 Feeling cramped 16(7.6) 13(12.5) 3(2.8) 0.008 Feeling less well 50(22.9) 29(27.1) 21(18.9) 0.19 Kessler-6 score ≥ 5 57(26.8) 33(32.0) 24(21.8)) 0.12 Sleep impairment 53(24.5) 30(28.6) 23(20.7) 0.20 Angina pectorisdestabilization 13(6.6) 8(7.9) 5(5.3) 0.57 Cancelled physical examination** 67(63.8) 40(65.6) 27(61.4) 0.68 Switched to Telehealth*** 16(17.0) 7(17.5) 9(16.7) 1 Coronavirus testing 7(3.2) 3(2.8) 4(3.6) 1 Lifestyle behaviours Cigarette smoking 36(16.4) 26(23.3) 10(9.3) 0.006 Cigarette smoking increase 11(30.6) 8(40.0) 3(18.8) 0.27 Decreased physical activity 96(44.2) 56(53.3) 40(35.7) 0.009 Screentime increase 98(45.0) 59(55.1) 39(35.1) 0.004 Alcohol intake increase 10(5.2) 5(5.3) 5(5.2) 1 Weight increase ≥ 2 kg 52(24.5) 28(26.9) 24(22.2) 0.52 * between Urban and Rural **from scheduled physical examination ***from cancelled scheduled physical examination

During the Covid-19 lockdown, rural residence is associated to healthier lifestyle behaviours in patients with chronic coronary syndrom