English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Aims The natural history of atrioventricular blocks (AVBs) in children is not completely clarified, with particular regard for isolated, acquired, and non-immune disorders. Moreover, there is still concern on when—and not on if—a pacemaker (PM) implantation is indicated. In this retrospective study, we investigated diagnostic and therapeutic approach to AVBs in children and we described complications occurred in PM recipients. Methods and results We analysed 73 patients with a diagnosis of AVB who were submitted to a regular follow-up between 2015 and 2020 at the Paediatric Cardiology and Cardiac Surgery Unit of an Italian referral centre. Forty-four patients (60%) were diagnosed with a complete AVB and after a mean follow-up of 8.2 ± 6.8 years, 35 patients (79.5%) had received a permanent PM. AVB was asymptomatic in 52 children (71.2%) and a congenital heart disease was present in 13 cases (17.8%). Anti-SSA/B autoantibodies were detected in eight patients (11%) with complete block and their prognostic role was substantially redefined. The mean interval between diagnosis and implantation and the complication rate in PM recipients were similar to data available on literature, regardless of the age at diagnosis. Conclusions From a diagnostic point of view, we identified several differences between partial and complete AVBs. As regards the timing of pacing therapy, the moment of implantation should be accurately chosen but should not depend only on the age at diagnosis or the presence of maternal autoantibodies, since the incidence of device-related complications was independent from those features.

422 Atrioventricular blocks in children: clinical aspects and special features in a cohort of Italian patients