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prevalence, scientific evidence is scarce and studies are needed to determine if IEAP could be useful in these individuals. Objectives: We sought to describe the clinical course and microbiological profile of BAV and MVP patients with IE and compare them with those of patients with and without IEAP indications. Methods: Data from the GAMES IE registry involving 27 Spanish hospitals were analyzed. From January 2008 to March 2015, 3120, consecutive IE patients were prospectively included in the registry. We selected: high-risk patients with indication of IEAP (Group 1, n=1115), patients without indication of IEAP (Group 2, n=1876), and patients with BAV (n=49) and MVP (n=80). Microbiological characteristics and adverse events due to IE during hospitalization were analyzed. BAV and MVP patients were compared to Groups 1 and 2. (Figure) Results: BAV and MVP patients exhibited higher incidence of Streptococcus viridans IE than patients from Group 2 (26.5 vs 11.5%, p<0.01) and (33.8 vs 11.5%, p<0.01), respectively. Moreover, BAV and MVP patients had a higher percentage of IE from suspected odontological origin in comparison to Group 2 (14.3 vs 5.2%, p<0.01) and (17.5 vs 5.2%, p<0.01), respectively. BAV patients suffered more intracardiac complications (53.1 vs 31.7%, p<0.01) and underwent cardiac surgery more frequently than Group 1 (73.5 vs 42.2%, p=0.01). MVP patients also showed more intracardiac complications than Group 1 (45 vs 31.7%, p<0.01). However, there were not statistically significant differences in cardiac surgery between both groups (p=0.541)

P4544Enterococcus faecalis endocarditis: prognostic factors, and 1-year survival vs propensity score matched patients with streptococcal endocarditis