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Download the Issue @ a Glance podcastSubscribe to the EHJ Podcast ![Graphic][1]  spite of all the progress made over the last decades,1 the management of acute coronary syndromes remains an important issue as they continue to be responsible for most of the morbidity and mortality in cardiovascular medicine.2 Acute coronary syndromes encompass ST-elevation (STEMI) and non-ST-elevation myocardial infarction (non-STEMI) as well as unstable angina.3 Today, patients with STEMI are treated urgently and effectively by primary percutaneous coronary interventions (pPCIs) in most countries.4 An issue that remains to be resolved is the management of STEMI patients with coronary lesions in the non-infarct-related artery. In the Editoru0027s Page ‘ Multivessel revascularization in ST-segment elevation myocardial infarction: where do we stand? ’, Thomas F. Luscher and Ronald Binder from the University Hospital of Zurich point out that it still remains unclear whether a multivessel intervention at the time of first presentation with or without the use of fractional flow reserve determinations, a staged procedure, or wait and see is the most appropriate approach to such patients.5 Based on current available evidence, they propose an algorithm for patients with STEMI and multivessel disease, but point out that additional trials are required to refine further the management of these patients that are at high risk.6The most recent progress made in the field of acute … [1]: /embed/inline-graphic-1.gif

The management of acute coronary syndromes: towards optimal treatment of STEMI and non-STEMI