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With great interest we read the manuscript published by Gratz et al. 1 addressing the important issue of quality-of-life (QoL) and its possible correlation to exercise capacity in patients with congenital heart disease (CHD). The majority of surprisingly high QoL scores were not correlated to exercise capacity as quantified by peak oxygen uptake (peakVO2).However, several questions have to be addressed concerning the manuscript. Gratz et al. showed unreliably high peakVO2 results with single values of more than 70 mL/kg/min. Applying our own recently published reference equations on these values would result in a peakVO2 of 170% as personally predicted …

Peak oxygen uptake and exercise capacity: a reliable predictor of quality of life?