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To illustrate the application of relative survival to observational studies in coronary heart disease (CHD) and potential advantages compared with all-cause survival methods. Survival after myocardial infarction (MI) is generally assessed using all-cause or cause-specific methods. Neither method is able to assess the impact of the disease or condition of interest in comparison with expected survival in a similar population. Relative survival, the ratio of the observed and the expected survival rates, is applied routinely in cancer studies and may improve on current methods for assessment of survival in CHD.

Relative survival: what can cardiovascular disease learn from cancer?