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One-lung ventilation (OLV) with general anaesthesia may increase adverse effects after thoracic surgery, specifically ventilator-induced lung injury. Spontaneous ventilation (SV) has no mechanical ventilation process, thus, we established a rabbit model to assess non-operative lung injury between OLV and SV.

The impact of spontaneous ventilation on non-operative lung injury in thoracic surgery: a randomized controlled rabbit model study